CHEMBL211976


SMILES O=C(NCCC1CCNCC1)[C@H]1CCCN1C(=O)[C@@H]1C[C@@H](O)CN1C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1
InChIKey KFVGSPFDTINYRJ-SXLOSVNLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 622.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.55 8.55 8.55 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.92 5.92 5.92 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.7 5.7 5.7 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.82 6.82 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database