CHEMBL212370


SMILES Clc1ccc(N2CCN(Cc3cn4ccccc4n3)CC2)cc1
InChIKey NSWRCNIUQFRZFO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 326.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.17 5.17 5.17 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.15 8.15 8.15 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.06 5.06 5.06 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.8 4.81 4.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.59 8.66 8.74 ChEMBL