CHEMBL214311


SMILES Clc1ccc(CNCC[C@H]2C[C@@H]2c2c[nH]cn2)cc1
InChIKey BOQXUEKBVIXPKQ-JSGCOSHPSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 275.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.43 7.43 7.43 ChEMBL
H3 HRH3 Human Histamine A pKi 8.44 8.44 8.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pIC50 6.07 6.07 6.07 ChEMBL
H1 HRH1 Human Histamine A pIC50 5.07 5.07 5.07 ChEMBL
H3 HRH3 Human Histamine A pIC50 8.07 8.07 8.07 ChEMBL