CLOMIPHENE


SMILES CCN(CC)CCOc1ccc(C(=C(Cl)c2ccccc2)c2ccccc2)cc1
InChIKey GKIRPKYJQBWNGO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 405.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 Drug Central
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.21 8.21 8.21 Drug Central
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.24 8.24 8.24 Drug Central
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.19 8.19 8.19 Drug Central
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.23 8.23 8.23 Drug Central
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.2 8.2 8.2 Drug Central
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.18 8.18 8.18 Drug Central
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.23 8.23 8.23 Drug Central
α2A ADA2A Human Adrenoceptors A pKi 8.19 8.19 8.19 Drug Central
α2B ADA2B Human Adrenoceptors A pKi 8.21 8.21 8.21 Drug Central
β3 ADRB3 Human Adrenoceptors A pKi 8.27 8.27 8.27 Drug Central
D3 DRD3 Human Dopamine A pKi 8.2 8.2 8.2 Drug Central
H1 HRH1 Human Histamine A pKi 8.29 8.29 8.29 Drug Central
NK2 NK2R Human Tachykinin A pKi 8.23 8.23 8.23 Drug Central
A3 AA3R Human Adenosine A pKi 8.26 8.26 8.26 Drug Central
α1B ADA1B Rat Adrenoceptors A pKi 8.25 8.25 8.25 Drug Central
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 Drug Central
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.71 5.71 5.71 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 8.18 8.18 8.18 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPS NPSR1 Human Neuropeptide S A Potency 5.0 5.0 5.0 ChEMBL