CHEMBL2365079


SMILES CCc1cc2c(c(C(F)(F)F)c1)C(=O)N[C@H]1CNC[C@H]21
InChIKey ZGBJXYZTHWMREU-KOLCDFICSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 284.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.0 7.0 7.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.37 8.37 8.37 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.22 6.22 6.22 ChEMBL