CHEMBL2164786


SMILES CCO/N=C1\C=C(C#Cc2ccccn2)CCC1F
InChIKey OXITTWFVOBVMDI-OBGWFSINSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 258.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.51 7.51 7.51 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pKd 7.16 7.16 7.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database