CHEMBL2365399


SMILES CCc1ccc(Cl)c2c1[C@H]1CNC[C@@H]1NC2=O
InChIKey DZCHRJUWBYFRSD-WPRPVWTQSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 250.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.26 7.26 7.26 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 5.63 5.63 5.63 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.96 7.96 7.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 5.78 5.78 5.78 ChEMBL