CHEMBL216629


SMILES COc1ccccc1CNCCCCCCN(C)CCCCCCCCN(C)CCCCCCN(CC(=O)N1c2ccccc2C(=O)Nc2cccnc21)CC(=O)N1c2ccccc2C(=O)Nc2cccnc21
InChIKey IRNCRYZAAPHVSP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 30
Molecular weight (Da) 992.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 5.6 5.6 5.6 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 7.73 7.73 7.73 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.34 8.34 8.34 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database