CHEMBL2181168


SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ncccc23)CC1
InChIKey BIAZRDQNRJRCRQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 461.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 9.59 9.59 9.59 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 8.34 8.34 8.34 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.99 5.99 5.99 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.25 5.25 5.25 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database