CHEMBL2387307


SMILES Cc1c(Cl)cc(NC(=O)Nc2ccc(OCCCN3CCCCC3)cc2)cc1Cl
InChIKey MHCPZQVCEMWMCX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 435.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 Q865E1 Rhesus macaque Histamine A pKi 7.74 7.74 7.74 ChEMBL
H3 HRH3 Rat Histamine A pKi 6.87 6.87 6.87 ChEMBL
H3 HRH3 Human Histamine A pKi 6.95 6.95 6.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pIC50 9.7 9.7 9.7 ChEMBL