L-692,429


SMILES O=C(CC(N)(C)C)N[C@@H]1CCc2c(N(C1=O)Cc1ccc(cc1)c1ccccc1c1nnn[nH]1)cccc2
InChIKey SBJLJOFPWOYATP-XMMPIXPASA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 509.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pKi 7.2 7.2 7.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pEC50 7.33 7.23 7.59 Guide to Pharmacology
ghrelin GHSR Rat Ghrelin A pEC50 7.22 7.22 7.22 Guide to Pharmacology
ghrelin GHSR Pig Ghrelin A pIC50 7.2 7.2 7.2 ChEMBL
ghrelin GHSR Rat Ghrelin A pEC50 7.22 7.22 7.22 ChEMBL
ghrelin GHSR Rat Ghrelin A pIC50 7.22 7.22 7.22 ChEMBL
ghrelin GHSR Human Ghrelin A pIC50 5.55 5.55 5.55 ChEMBL
AT1 AGTR1 Human Angiotensin A pIC50 5.44 5.44 5.44 ChEMBL
GHRH GHRHR Rat Glucagon B1 pEC50 7.22 7.22 7.22 ChEMBL