CHEMBL2204343


SMILES O=C(CCCN1CC[Si](O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1
InChIKey IMFLKRNUSHCDBK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 391.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.78 7.78 7.78 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.85 7.85 7.85 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.79 6.79 6.79 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.32 8.32 8.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.26 9.26 9.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database