CHEMBL2205827


SMILES COc1ccc(CN2C3C4C5CC6C7C5C3C7C2(O)C64)cc1OC
InChIKey MGYAQEPRQTVZOM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 325.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.56 5.56 5.56 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.38 5.38 5.38 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.94 5.94 5.94 ChEMBL
H2 HRH2 Human Histamine A pKi 5.45 5.45 5.45 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.44 5.44 5.44 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.91 5.91 5.91 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.76 5.76 5.76 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.83 5.83 5.83 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.34 5.34 5.34 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.38 5.38 5.38 ChEMBL
κ OPRK Human Opioid A pKi 5.94 5.94 5.94 ChEMBL
μ OPRM Human Opioid A pKi 5.9 5.9 5.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database