CHEMBL2397915


SMILES O=C1c2cc(C(F)(F)F)ccc2C[C@@H]2CNCCN12
InChIKey KGYOIHNXJRJXJD-SNVBAGLBSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 270.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.41 7.41 7.41 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.97 6.97 6.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.75 7.75 7.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.97 6.97 6.97 ChEMBL