L-CCG-I


SMILES N[C@@H]([C@H]1C[C@@H]1C(=O)O)C(=O)O
InChIKey GZOVEPYOCJWRFC-HZLVTQRSSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 159.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.3 6.3 6.3 Guide to Pharmacology
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.4 7.4 7.4 Guide to Pharmacology
mGlu7 GRM7 Human Metabotropic glutamate C pKi 4.3 4.3 4.3 Guide to Pharmacology
mGlu3 GRM3 Rat Metabotropic glutamate C pKi 6.5 6.5 6.5 Guide to Pharmacology
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 6.8 6.9 7.0 Guide to Pharmacology
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 5.6 5.6 5.6 Guide to Pharmacology
mGlu8 GRM8 Human Metabotropic glutamate C pKi 5.47 5.47 5.47 ChEMBL
mGlu6 GRM6 Human Metabotropic glutamate C pKi 5.24 5.24 5.24 ChEMBL
mGlu1 GRM1 Human Metabotropic glutamate C pKi 4.3 4.3 4.3 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.31 6.31 6.31 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pKi 5.51 5.51 5.51 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.36 6.36 6.36 ChEMBL
mGlu4 GRM4 Human Metabotropic glutamate C pKi 4.3 4.3 4.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Human Metabotropic glutamate C pEC50 6.2 6.2 6.2 Guide to Pharmacology
mGlu8 GRM8 Human Metabotropic glutamate C pIC50 6.1 6.2 6.3 Guide to Pharmacology
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 5.8 5.8 5.8 Guide to Pharmacology
mGlu6 GRM6 Rat Metabotropic glutamate C pEC50 5.2 5.2 5.2 Guide to Pharmacology
mGlu8 GRM8 Rat Metabotropic glutamate C pEC50 6.2 6.2 6.2 Guide to Pharmacology
mGlu4 GRM4 Rat Metabotropic glutamate C pIC50 4.3 4.65 5.0 Guide to Pharmacology
mGlu6 GRM6 Rat Metabotropic glutamate C pEC50 6.22 6.22 6.22 ChEMBL
mGlu8 GRM8 Rat Metabotropic glutamate C pEC50 6.4 6.4 6.4 ChEMBL
mGlu7 GRM7 Rat Metabotropic glutamate C pEC50 4.33 4.33 4.33 ChEMBL
mGlu4 GRM4 Rat Metabotropic glutamate C pEC50 5.4 5.4 5.4 ChEMBL
mGlu3 GRM3 Rat Metabotropic glutamate C pEC50 6.22 6.22 6.22 ChEMBL
mGlu1 GRM1 Rat Metabotropic glutamate C pEC50 4.64 4.64 4.64 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 6.12 6.32 6.52 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.42 6.42 6.42 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 4.77 4.77 4.77 ChEMBL