CHEMBL2207633


SMILES COc1ccccc1N1CCN(Cc2cc(C#Cc3ccccc3)c3cccccc2-3)CC1
InChIKey KMVWYPYWHLOVLW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 432.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.89 5.89 5.89 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.8 7.8 7.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.17 7.18 7.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database