DIMETHINDENE


SMILES CC(C1=C(CCN(C)C)Cc2ccccc21)c1ccccn1
InChIKey MVMQESMQSYOVGV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 292.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.1 6.1 6.1 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.39 6.39 6.39 ChEMBL
H1 HRH1 Human Histamine A pKi 9.16 9.16 9.16 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.72 6.72 6.72 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.35 7.35 7.35 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.58 6.58 6.58 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.18 8.18 8.18 Drug Central
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.13 8.13 8.13 Drug Central
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.17 8.17 8.17 Drug Central
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.19 8.19 8.19 Drug Central
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.21 8.21 8.21 Drug Central
H1 HRH1 Human Histamine A pKi 8.04 8.04 8.04 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database