CHEMBL240215


SMILES O=C1NCN(c2ccccc2)C12CCN(Cc1c(Cl)cccc1Cl)CC2
InChIKey KEDOVCNKPNVSAY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 389.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.64 8.64 8.64 ChEMBL
δ OPRD Human Opioid A pKi 5.79 5.79 5.79 ChEMBL
κ OPRK Human Opioid A pKi 7.28 7.28 7.28 ChEMBL
μ OPRM Human Opioid A pKi 7.53 7.54 7.54 ChEMBL
δ OPRD Human Opioid A pKi 5.79 5.79 5.79 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.64 8.64 8.64 PDSP Ki database
κ OPRK Human Opioid A pKi 7.28 7.28 7.28 PDSP Ki database
μ OPRM Human Opioid A pKi 7.54 7.54 7.54 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database