CHEMBL241272


SMILES O=C1NCN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2
InChIKey VZIPEFHBXCQMEJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 465.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.17 8.17 8.17 ChEMBL
δ OPRD Human Opioid A pKi 3.82 3.82 3.82 ChEMBL
κ OPRK Human Opioid A pKi 5.23 5.23 5.23 ChEMBL
μ OPRM Human Opioid A pKi 5.23 5.72 6.22 ChEMBL
NOP OPRX Human Opioid A pKi 8.17 8.17 8.17 PDSP Ki database
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
κ OPRK Human Opioid A pKi 5.23 5.23 5.23 PDSP Ki database
μ OPRM Human Opioid A pKi 5.23 5.23 5.23 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database