CHEMBL242265


SMILES C[C@@H](Oc1ccccc1-c1ccccc1)C1=NCCN1
InChIKey OGOLMGZJNRNULQ-CYBMUJFWSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 266.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.9 5.9 5.9 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.01 6.01 6.01 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.73 6.73 6.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 4.0 4.0 4.0 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 6.95 6.95 6.95 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 4.54 4.54 4.54 ChEMBL