Oliceridine


SMILES COc1ccsc1CNCC[C@@]1(c2ccccn2)CCOC2(CCCC2)C1
InChIKey DMNOVGJWPASQDL-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 5.55 5.55 5.55 ChEMBL
κ OPRK Human Opioid A pEC50 5.85 5.85 5.85 ChEMBL
μ OPRM Human Opioid A pEC50 7.3 7.83 8.1 ChEMBL
μ OPRM Human Opioid A pKi 8.22 8.22 8.22 ChEMBL
NOP OPRX Human Opioid A pEC50 7.13 7.13 7.13 Drug Central
μ OPRM Human Opioid A pKi 7.09 7.09 7.09 Drug Central