(+)-MCPG


SMILES OC(=O)c1ccc(cc1)[C@@](C(=O)O)(N)C
InChIKey DNCAZYRLRMTVSF-JTQLQIEISA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 209.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 3.8 3.8 3.8 Guide to Pharmacology
mGlu3 GRM3 Human Metabotropic glutamate C pKi 3.8 3.8 3.8 Guide to Pharmacology
mGlu7 GRM7 Human Metabotropic glutamate C pKi 3.2 3.2 3.2 Guide to Pharmacology
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 4.6 4.6 4.6 Guide to Pharmacology
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 3.8 3.8 3.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 3.7 3.7 3.7 Guide to Pharmacology
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 5.37 5.37 5.37 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 5.37 5.37 5.37 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 5.4 5.4 5.4 ChEMBL