CHEMBL2432051


SMILES COc1cc(CN[C@H]2C3C4CC5C6C4CC3C6C52)cc(OC)c1OC
InChIKey CPLYGLAQLNAQOI-SEDVZXITSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 341.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.18 6.18 6.18 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.64 5.64 5.64 ChEMBL
H2 HRH2 Human Histamine A pKi 5.76 5.76 5.76 ChEMBL
H1 HRH1 Human Histamine A pKi 5.25 5.25 5.25 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.71 5.71 5.71 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.51 5.51 5.51 ChEMBL
κ OPRK Human Opioid A pKi 5.7 5.7 5.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.98 5.98 5.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database