CHEMBL2448129


SMILES CN1c2ccc(Cl)cc2C(c2ccccc2)=NC[C@H]1CCNC(=O)c1cccs1
InChIKey JEZGMXQLYTYHBX-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 423.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 8.18 8.18 8.18 ChEMBL
δ OPRD Human Opioid A pKi 6.12 6.12 6.12 ChEMBL
κ OPRK Human Opioid A pKi 9.1 9.1 9.1 ChEMBL
μ OPRM Human Opioid A pKi 7.48 7.48 7.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database