metopimazine


SMILES NC(=O)C1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)S(=O)(=O)C
InChIKey BQDBKDMTIJBJLA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 445.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 8.08 8.08 8.08 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.21 9.21 9.21 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.04 8.04 8.04 Drug Central
H1 HRH1 Human Histamine A pKi 8.09 8.09 8.09 Drug Central
D2 DRD2 Human Dopamine A pKi 7.99 7.99 7.99 Drug Central
D2 DRD2 Human Dopamine A pKi 10.15 10.15 10.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database