CHEMBL2312638


SMILES O=S(=O)(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2cccnc12
InChIKey ZQUOAIISQYYMQZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 492.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.95 6.95 6.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database