CHEMBL2312642


SMILES O=S(=O)(NCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc2ncccc2c1
InChIKey UNXSKPWKGQDDCI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 478.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database