CHEMBL2312936


SMILES O=S(=O)(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cnc2ccc(Cl)cc2c1
InChIKey WNGWFFRYQWCYAB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 526.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.39 7.39 7.39 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.38 7.38 7.38 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database