Biased Signaling Atlas

OLICERIDINE

Agent/drug
Bioactivity

OLICERIDINE

SMILES	COc1ccsc1CNCC[C@@]1(c2ccccn2)CCOC2(CCCC2)C1
InChIKey	DMNOVGJWPASQDL-OAQYLSRUSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	386.2

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb
Structure pdb	8EFB

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

μ	OPRM	Human	Opioid	A	pKi	8.22	8.47	8.84	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	8.09	8.09	8.09	Drug Central
D₂	DRD2	Human	Dopamine	A	pKi	4.08	4.08	4.08	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	5.16	5.16	5.16	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	5.55	5.55	5.55	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	5.85	5.85	5.85	ChEMBL
μ	OPRM	Mouse	Opioid	A	pEC50	7.23	7.78	8.62	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	7.30	8.06	8.74	ChEMBL
NOP	OPRX	Human	Opioid	A	pEC50	8.13	8.13	8.13	Drug Central

Showing 1 to 5 of 5 entries

OLICERIDINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved Yes

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb
Structure pdb	8EFB

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

OPRM	μ receptor	Opioid receptors	Peptide receptors	Class A	Pain, unspecified	MG3Z		0.609	4	Yes

Showing 1 to 1 of 1 entry