MPPG


SMILES OC(=O)C(c1ccc(cc1)P(=O)(O)O)(N)C
InChIKey PAONCRJPUQXPRW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 245.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu7 GRM7 Human Metabotropic glutamate C pKi 3.8 3.8 3.8 Guide to Pharmacology
mGlu4 GRM4 Rat Metabotropic glutamate C pKi 4.2 4.2 4.2 Guide to Pharmacology
mGlu2 GRM2 Human Metabotropic glutamate C pKi 4.96 4.96 4.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Human Metabotropic glutamate C pIC50 3.3 3.3 3.3 Guide to Pharmacology
mGlu8 GRM8 Human Metabotropic glutamate C pIC50 4.33 4.33 4.33 Guide to Pharmacology