CHEMBL251555


SMILES CS(=O)(=O)Nc1cc(C[C@@H](O)CN[C@@H](CCc2ccccc2)c2ccc(OC(F)F)c(OC(F)F)c2)ccc1O
InChIKey GRSIQKKNSPHJED-RTWAWAEBSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 15
Molecular weight (Da) 586.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 6.31 6.31 6.31 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 7.15 7.15 7.15 ChEMBL
β3 ADRB3 Human Adrenoceptors A pKi 7.23 7.23 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database