CHEMBL234440


SMILES CN(C)C1(CNCCC2CCOCC2)COc2cc(Cl)c(Cl)cc2OC1
InChIKey RXLCWZMWTUZMFM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 402.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.66 9.66 9.66 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.92 9.92 9.92 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.74 8.74 8.74 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.74 8.74 8.74 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.92 9.92 9.92 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.66 9.66 9.66 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database