N(6)-cyclohexyladenosine


SMILES OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCCC1
InChIKey SZBULDQSDUXAPJ-XNIJJKJLSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Human Adenosine A pKi 5.9 5.9 5.9 Guide to Pharmacology
A2B AA2BR Human Adenosine A pKi 3.8 3.8 3.8 Guide to Pharmacology
A3 AA3R Human Adenosine A pKi 5.99 5.99 5.99 Guide to Pharmacology
A1 AA1R Rat Adenosine A pKi 9.07 9.07 9.07 Guide to Pharmacology
A3 AA3R Rat Adenosine A pKi 6.75 6.75 6.75 Guide to Pharmacology
A2A AA2AR Guinea pig Adenosine A pKi 8.3 8.3 8.3 ChEMBL
A1 AA1R Bovine Adenosine A pKi 8.6 8.75 8.89 ChEMBL
A2A AA2AR Rat Adenosine A pKi 6.22 6.22 6.22 ChEMBL
A1 AA1R Rat Adenosine A pKi 7.68 8.73 9.07 ChEMBL
A1 AA1R Rat Adenosine A pKd 8.89 8.89 8.89 ChEMBL
A2A AA2AR Human Adenosine A pKi 6.12 6.12 6.12 ChEMBL
A3 AA3R Rat Adenosine A pKi 7.6 7.6 7.6 ChEMBL
A2A AA2AR Rat Adenosine A pKi 6.34 6.34 6.34 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A1 AA1R Chicken Adenosine A pIC50 8.6 8.6 8.6 ChEMBL
A1 AA1R Rat Adenosine A pIC50 8.3 8.71 9.07 ChEMBL