CHEMBL256637
SMILES | COc1cc(CN2CCN(c3ccc(Cl)cc3)CC2)c(OCCF)cc1OC |
InChIKey | XBXGSRGFTFVODB-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 0 |
Rotatable bonds | 8 |
Molecular weight (Da) | 408.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT2A | 5HT2A | Pig | 5-Hydroxytryptamine | A | pKi | 7.0 | 7.0 | 7.0 | ChEMBL |
D1 | DRD1 | Pig | Dopamine | A | pKi | 5.46 | 5.46 | 5.46 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 8.77 | 8.77 | 8.77 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 5.41 | 5.41 | 5.41 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.12 | 6.12 | 6.12 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |