CHEMBL256804


SMILES CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3ccc(F)c(F)c3)CC2)CC1
InChIKey PIKIDBPDYRQPFX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 472.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.02 6.62 7.22 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.14 7.97 8.8 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.29 7.87 8.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.9 7.08 7.27 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.02 6.62 7.22 PDSP Ki database
α1D ADA1D Human Adrenoceptors A pKi 7.14 7.92 8.8 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.9 7.08 7.27 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database