neuropeptide FF
| SMILES | None |
| InChIKey | None |
| Sequence | FLFQPQRF |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Endogenous |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| NPFF2 | NPFF2 | Human | Neuropeptide FF/neuropeptide AF | A | pKi | 9.7 | 9.7 | 9.7 | Guide to Pharmacology |
| NPFF2 | NPFF2 | Mouse | Neuropeptide FF/neuropeptide AF | A | pKi | 8.96 | 8.96 | 8.96 | ChEMBL |
| NPFF2 | NPFF2 | Rat | Neuropeptide FF/neuropeptide AF | A | pKi | 9.68 | 9.68 | 9.68 | ChEMBL |
| NPFF1 | NPFF1 | Human | Neuropeptide FF/neuropeptide AF | A | pKi | 10.22 | 10.22 | 10.22 | ChEMBL |
| NPFF1 | NPFF1 | Human | Neuropeptide FF/neuropeptide AF | A | pKd | 8.95 | 8.95 | 8.95 | ChEMBL |
| NPFF2 | NPFF2 | Human | Neuropeptide FF/neuropeptide AF | A | pKi | 8.92 | 9.81 | 10.7 | ChEMBL |
| NPFF2 | NPFF2 | Human | Neuropeptide FF/neuropeptide AF | A | pKd | 9.43 | 9.55 | 9.68 | ChEMBL |
| NPFF1 | NPFF1 | Human | Neuropeptide FF/neuropeptide AF | A | pKi | 8.5 | 9.2 | 9.9 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MAS1 | MAS | Mouse | A orphans | A | pEC50 | 6.4 | 6.4 | 6.4 | Guide to Pharmacology |
| NPFF1 | NPFF1 | Human | Neuropeptide FF/neuropeptide AF | A | pEC50 | 6.56 | 6.64 | 6.8 | ChEMBL |
| NPFF2 | NPFF2 | Human | Neuropeptide FF/neuropeptide AF | A | pEC50 | 6.21 | 7.4 | 8.57 | ChEMBL |