CHEMBL236861


SMILES NC1CCC(CC2CCC(N(C/C(Cl)=C/c3ccccc3)C(=O)CCCc3c[nH]c4ccccc34)CC2)CC1
InChIKey CRXBLMIVMQUQBT-IADYIPOJSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 545.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Mouse Melanocortin A pKi 5.64 6.0 6.29 ChEMBL
MC5 MC5R Human Melanocortin A pKi 4.33 5.09 5.5 ChEMBL
MC3 MC3R Human Melanocortin A pKi 4.48 4.72 5.15 ChEMBL
MC4 MC4R Human Melanocortin A pKi 5.22 5.37 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database