CHEMBL26135
SMILES | COc1cccc(C(=O)CCCCN2CCN(c3ccccc3OC)CC2)c1 |
InChIKey | ZWHFVXLGTWFJQQ-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 0 |
Rotatable bonds | 9 |
Molecular weight (Da) | 382.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT7 | 5HT7R | Rat | 5-Hydroxytryptamine | A | pKi | 7.07 | 7.07 | 7.07 | ChEMBL |
D2 | DRD2 | Rat | Dopamine | A | pKi | 7.25 | 7.25 | 7.25 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.37 | 7.37 | 7.37 | ChEMBL |
5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pKi | 8.47 | 8.47 | 8.47 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |