CHEMBL26483


SMILES O=C(CN1CN(c2ccccc2)C2(CCN(C3CCc4cccc(Cl)c4C3)CC2)C1=O)c1ccccc1
InChIKey XDBSOVFDSPYHQJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 513.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.82 7.82 7.82 ChEMBL
δ OPRD Human Opioid A pKi 6.29 6.29 6.29 ChEMBL
κ OPRK Human Opioid A pKi 7.54 7.54 7.54 ChEMBL
μ OPRM Human Opioid A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database