CHEMBL262865


SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
InChIKey ZCFHOMLAFTWDFM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 354.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 8.34 8.35 8.36 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 6.02 6.05 6.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Rat Cannabinoid A pEC50 8.8 8.8 8.8 ChEMBL
CB2 CNR2 Human Cannabinoid A pEC50 7.8 8.31 9.28 ChEMBL
CB2 CNR2 Human Cannabinoid A pIC50 9.11 9.11 9.11 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 6.48 6.48 6.48 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 6.09 6.09 6.09 ChEMBL