CHEMBL266647


SMILES CC(C)C[C@H](NC(=O)CCN(C)C)c1cc(Cl)ccc1N1CCN(C(=O)[C@H](C)Cc2ccc(Cl)cc2)CC1
InChIKey NICHJJOSEXYBED-AMGIVPHBSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 560.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Mouse Melanocortin A pKi 7.75 7.75 7.75 ChEMBL
MC3 MC3R Mouse Melanocortin A pKi 6.47 6.47 6.47 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.22 6.22 6.22 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.15 6.15 6.15 ChEMBL
ghrelin GHSR Human Ghrelin A pKi 6.34 6.34 6.34 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.47 8.47 8.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pEC50 6.14 6.14 6.14 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 6.03 6.03 6.03 ChEMBL