CHEMBL263700


SMILES CN(C)CCc1cn(C(=O)c2ccccc2)c2ccc(O)cc12
InChIKey UJELDYRUBKQNKE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 308.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Rat 5-Hydroxytryptamine A pKi 5.35 5.35 5.35 ChEMBL
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.27 7.27 7.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database