CHEMBL26917


SMILES Cc1ccc(OCC(O)CNC(C)C)c2c1CCC2
InChIKey JLECPPBHIADANW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 263.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 B0FL73 Guinea pig Adrenoceptors A pKd 7.01 7.01 7.01 ChEMBL
β2 ADRB2 Guinea pig Adrenoceptors A pKd 7.5 7.5 7.5 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 4.72 4.72 4.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Bovine Adrenoceptors A pIC50 7.75 7.75 7.75 ChEMBL
β1 ADRB1 Human Adrenoceptors A pIC50 6.73 6.73 6.73 ChEMBL