CHEMBL2397478


SMILES C#CC1=CC[C@@H](N(CCC)CCCCNC(=O)c2ccc(OCCCc3cnn(CCCC)n3)c(OC)c2)CC1
InChIKey HKOJNCZKZSYFEQ-GDLZYMKVSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 18
Molecular weight (Da) 549.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.89 4.89 4.89 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.52 7.52 7.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.0 9.0 9.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.22 8.64 9.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database