CHEMBL280827


SMILES Cc1cccc2c1CCCC2N1CCC2(CC1)C(=O)NCN2c1ccccc1
InChIKey PYQRZQXALHGAGL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.85 8.85 8.85 ChEMBL
δ OPRD Human Opioid A pKi 6.34 6.34 6.34 ChEMBL
κ OPRK Human Opioid A pKi 7.36 7.36 7.36 ChEMBL
μ OPRM Human Opioid A pKi 7.5 7.5 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 6.29 6.29 6.29 ChEMBL
μ OPRM Human Opioid A pEC50 5.43 5.43 5.43 ChEMBL