CHEMBL28209


SMILES COc1ccccc1N1CCN(CCCCC2CCCc3c(OC)cccc32)CC1
InChIKey FKAHRAYTSLFRRL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 408.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.3 8.3 8.3 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.37 7.37 7.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 7.81 7.81 7.81 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 8.76 8.76 8.76 ChEMBL