CHEMBL2435409


SMILES O=C1CCCC2(CCN(c3nc4ccccc4o3)CC2)N1Cc1cccc2[nH]ccc12
InChIKey UXTQDECOFADUAA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.7 7.71 7.73 ChEMBL
OX1 OX1R Human Orexin A pKd 7.44 7.44 7.44 ChEMBL
OX2 OX2R Human Orexin A pKi 8.5 8.51 8.52 ChEMBL
OX2 OX2R Human Orexin A pKd 7.92 7.92 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database