CHEMBL2435413


SMILES Cc1ccc(C)c(CN2C(=O)CCCC23CCN(c2cnc4ccccc4n2)CC3)c1
InChIKey XOEYXHCZYQOOHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.11 7.17 7.23 ChEMBL
OX1 OX1R Human Orexin A pKd 7.0 7.0 7.0 ChEMBL
OX2 OX2R Human Orexin A pKi 7.8 7.84 7.89 ChEMBL
OX2 OX2R Human Orexin A pKd 7.44 7.44 7.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database