CHEMBL2435414


SMILES O=C1N(Cc2ccccc2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey GFXQGGGPTWXAKG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.81 5.82 5.83 ChEMBL
OX1 OX1R Human Orexin A pKd 5.88 5.88 5.88 ChEMBL
OX2 OX2R Human Orexin A pKi 6.43 6.58 6.74 ChEMBL
OX2 OX2R Human Orexin A pKd 6.52 6.52 6.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database