CHEMBL282829


SMILES CCc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1
InChIKey FKHBXKAEVUTBRK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 320.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.3 8.3 8.3 ChEMBL
D3 DRD3 Rat Dopamine A pKi 5.77 5.77 5.77 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.35 5.35 5.35 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database